Monocyte-erythrocyte interaction in vitro in immune hemolytic anemias

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Monocyte-erythrocyte interaction in vitro in immune hemolytic anemias .

Monocyte recognition of immunoprotein-coated erythrocytes in vitro was studied in 21 patients with immune hemolytic anemia. Simultaneous assessment of immunoglobulin and complement components on the patients' erythrocytes was performed. The patients were heterogeneous in relation to associated diseases, therapy, and duration of disease state; 15 were studied within 1 mo of diagnosis and 4 addi...

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Monocyte - Erythrocyte Interaction In Vitro in Immune

Monocyte recognition of i mmunoprotei ncoated erythrocytes in vitro was studied in 21 patients with immune hemolytic anemia. Simultaneous assessment of immunoglobulin and complement components on the patients’ erythrocytes was performed. The patients were heterogeneous in relation to associated diseases, therapy, and duration of disease state; 15 were studied within 1 mo of diagnosis and 4 addi...

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Sucrose density gradient analysis of erythrocyte membranes in hemolytic anemias.

To investigate the membrane abnormalities that may play a pathophysiologic role in several hemolytic anemias we determined the density distribution on sucrose density gradients of human red blood cell (RBC) membranes from patients with these disorders, from normal controls, and from incubated normal RBC. We analyzed the fractions for membrane-adsorbed hemoglobin (Hb), globin, and nonglobin cyto...

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Pulmonary hypertension in hemolytic anemias

Pulmonary hypertension (PH) has been reported with nearly all forms of the inherited as well as the acquired hemolytic anemias. Recent research investigating the pathophysiology of PH in sickle cell disease and thalassemia has helped elucidate the central role of hemolysis-mediated endothelial dysfunction in the development of PH in these populations. Although the most appropriate treatment of ...

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ژورنال

عنوان ژورنال: Blood

سال: 1977

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v50.5.889.889